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Search Results for " dopamine receptor "

20

Compounds

Cat No. Product Name Synonyms Targets
T60075 Dopamine D2 receptor agonist-2 Dopamine D2 Receptor Dopamine Receptor
Dopamine D2 receptor agonist-2 (Dopamine D2 Receptor) is a ligand targeting the dopamine D2 receptor.
T11077 Dopamine D2 receptor antagonist-1 Others
Dopamine D2 Receptor Antagonist-1 functions as a negative allosteric modulator (NAM) of the dopamine D2 receptor (D2R), demonstrating sub-millimolar affinity.
T3187 Fluoroclebopride Dopamine Receptor
Fluoroclebopride is a dopamine (DA) D2 receptor ligand.
T1644 Dopamine hydrochloride Dopamine HCl,ASL279 Ferroptosis , Dopamine Receptor , 5-HT Receptor , Endogenous Metabolite
Dopamine hydrochloride (ASL279) is a naturally occurring catecholamine formed by decarboxylation of dihydroxyphenylalanine and a precursor of norepinephrine and epinephrine. Dopamine hydrochloride binds to alpha-1- and b...
T4007 Eticlopride hydrochloride Dopamine Receptor
Eticlopride, an antipsychotic, is a Selective dopamine D2/D3 receptor antagonist (Ki: 0.5/0.16 nM).
T0280 Spiperone Spiroperidol,Spiropitan Dopamine Receptor
Spiperone (Spiropitan) is a spiro butyrophenone analog similar to HALOPERIDOL and other related compounds. It has been recommended in the treatment of SCHIZOPHRENIA.
T7635 Raclopride Dopamine Receptor
Raclopride is a selective antagonist of dopamine D2/D3 receptor.
T9081 FAUC 346 Dopamine Receptor
FAUC 346 is a highly selective D3 partial agonist with EC50 of 1.5 nM.
T9272 Xaliproden hydrochloride Dopamine Receptor , 5-HT Receptor
Xaliproden is a compound that mimics the effects of nerve growth factor and is also a serotonin 5-HT1A receptor agonist.
T15270 Fananserin RP 62203 Dopamine Receptor , 5-HT Receptor
Fananserin is an effective, selective and oral active antagonist of 5-HT2 (Ki = 0.37 nM for the rat 5-HT2A). Fananserin is an antagonist of human D4 receptor (Ki = 2.93 nM).
T83776 Dopamine D3 Receptor Agonist 13a
Dopamine D3 receptor agonist 13a selectively targets the dopamine D3 receptor over dopamine D1, D2, and D4 receptors, with affinities (Ki values) of 0.14, 4,600, 2.85, and 756 nM, respectively. It also interacts with ser...
T9228 Propionylpromazine hydrochloride Propiopromazine hydrochloride Dopamine Receptor
Propionylpromazine hydrochloride (Propiopromazine hydrochloride) is a dopamine receptor D2 (DRD2) antagonist.
T62946 Dopamine D3 receptor antagonist-2
Dopamine D3 receptor antagonist-2 is a dopamine D3 receptor selective (Ki=2.16 nM) or multi-targeting dual ligand that shows potential effects in CNS disorders.
T64024 Dopamine D3 receptor antagonist-1
Dopamine D3 receptor antagonist-1 is a dopamine D3 receptor selective or multi-targeting ligand with a Ki value of 1.58 nM that has demonstrated therapeutic potential for central nervous system disorders.
T23380 Sonepiprazole Dopamine Receptor
Sonepiprazole (PNU-101387G) is a chemical compound known for its selective antagonistic properties toward D4 dopamine receptors, exhibiting dissociation constants (Kis) of 3.6 nM and 10.1 nM for rat D4 (rD4) and human D4...
T19680 Zotepine Dopamine Receptor , 5-HT Receptor , Adrenergic Receptor , Histamine Receptor
Zotepine, an antipsychotic agent, is a potent antagonist of 5-HT2A, 5-HT2C, Histamine H1, α1-adrenergic, and Dopamine D2 receptors, with Kds of 2.6 nM, 3.2 nM, 3.3 nM, 7.3 nM, and 8 nM, respectively. Zotepine is a second...
T21629 Loxapine Dopamine Receptor , 5-HT Receptor
Loxapine is a D2DR and D4DR inhibitor, serotonergic receptor antagonist and also a dibenzoxazepine anti-psychotic agent,used primarily in the treatment of schizophrenia. The drug is a member of the dibenzoxazepine class ...
TQ0084 Lumateperone Tosylate ITI-007 Dopamine Receptor , 5-HT Receptor
lumateperone Tosylate (ITI-007) is a 5-HT2A receptor antagonist (Ki: 0.54 nM), a SERT blocker (Ki: 61 nM), a partial agonist of presynaptic D2 receptors and an antagonist of postsynaptic D2 receptors (Ki: 32 nM).
T16392 ONC206 Dopamine Receptor
ONC206, an analogue of the TRAIL inducer ONC201, acts as a selective antagonist of the D2-like dopamine receptors (DRD2/3/4) at nanomolar concentrations and possesses broad-spectrum anti-tumor activity.
T4S0779 D-tetrahydropalmatine Others , Dopamine Receptor
D-Tetrahydropalmatine is a organic cation transporter 1 (OCT1) inhibitor, it can obviously inhibit the uptake of monocrotaline (MCT) in MDCK-hOCT1 cells and isolate rat primary hepatocytes, and attenuate the viability re...
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